Oligo X Platform
About OligoMaker X Platform
The OligoMaker X Platform enables you to synthesize 12 to 1536 primers and probes simultaneously in a single run, utilizing a 96 or 384-well plate format for maximum efficiency. After synthesis, the column holder facilitates a seamless transition to the next step in the workup process.
A key feature of the OligoMaker X is our innovative “weekend wash” system. After each synthesis, all valves, tubing, and nozzles are automatically flushed with acetonitrile, extending the lifespan of the components and preventing clogging in the tubing—ensuring reliable, uninterrupted performance.
Key Features
- Synthesis Columns or Plates
- User-friendly operation
- Low Maintenance
- Small footprint
OligoMaker X12
The DNA / RNA Synthesizer OligoMaker X12/6 (OM-X12) is a flexible 12-channel oligonucleotide synthesizer with 6 base positions. Can easily be upgraded to 14 base positions.
- OligoMaker X12 is compact (80cm x 35cm x 35cm) and easy to operate.
- OligoMaker X12 can synthesize up to 12 oligos (20-mer) in about 1 hour.
- OligoMaker X12 is suitable for the smaller labs at the universities, where you might have a limited amount of amidite solution.
- Larger oligo houses can also benefit from this small and flexible synthesizer among all the high throughput machines.
- Direct injection of reagent from the valve into the synthesis column.
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | From 1 to 12 primers in one run – all +150-mer |
| Scale of synthesis | 10, 50nmol, 0.2, 1 and 3μmol scale |
| Support material | CPG or Universal support in standard columns |
| Standard equipment for amidites | 4 x 60-ml bottles + 2 x 10-ml |
| Up to 8 Extra amidite positions | 10-ml bottles |
| Standard 1 wash position | Acetonitrile – 450-ml |
| Standard 1 activator position | Activator – 180-ml |
| Standard 1 deblocking position | Deblocking – 450-ml |
| Standard 1 Ox position | Oxidizer – 180-ml |
| Standard Cap A position | Capping simultaneously with Cap B – 180-ml |
| Standard Cap B position | Capping simultaneously with Cap A – 180-ml |
| Ox2 position | Option – 30-ml bottle |
| Trityl monitoring | Trityl observation is possible after each cycle, coupling yield 99.0-99.5% |
| Only one gas connection | One gas for making pressure in the bottles and purging during synthesis |
| Instrument dimensions | 800 x 350 x 350 mm (L x W x H) |
| Cleaning | Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within a few minutes |
| Spare parts | Spare parts are in stock |
| Power | 110/115V or 220/240V |
| Safety | Overflowing by accident is directed to waste container |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marking |
| Service | On-call service |
OligoMaker X48
The DNA / RNA Synthesizer OligoMaker X48 (OM-X48) is a flexible oligonucleotide synthesizer with 4 base positions. Can easily be upgraded with 5 base positions
- OligoMaker X48 is compact (100cm x 55cm x 60cm) and easy to operate.
- OligoMaker X48 can synthesize up to 48 oligos (20-mer) in about 2 hour.
- OligoMaker X48 is ideal for research institutions that require increased flexibility to handle primers and probes, e.g smaller diagnostic company.
- Larger oligo production facilities can integrate the OligoMaker X48 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
- Direct injection of reagent from the valve into the synthesis column or plates.
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | From 1 to 48 primers in one run – all +150-mer |
| Scale of synthesis | 10, 50nmol, 0.2, 1 and 3μmol scale |
| Support material | CPG or Universal support in standard columns |
| Standard equipment for amidites | 4 x 120-ml bottles + 2 x 10-ml |
| Up to 8 Extra amidite positions | 10-ml bottles |
| Standard 2 activator positions | Activating in parallel |
| Standard 1 wash position | Washing |
| Standard 1 deblocking positions | Deblocking |
| Standard 1 Ox position | Oxidizer |
| Standard Cap A position | Capping simultaneously with Cap B |
| Standard Cap B position | Capping simultaneously with Cap A |
| Free position | Custom specified |
| Trityl monitoring | Trityl observation is possible after each cycle, coupling yield 99.0-99.5% |
| Automatic Wash and Purge System | Automatically wash and purge all nozzles after synthesis |
| Pressure on reagents | Each bottle can be pressurized and depressurized individually |
| Only one gas connection | One gas for making pressure in the bottles and purging during synthesis |
| Instrument – and Cleaning | 1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within a few minutes |
| Spare parts | Spare parts are in stock |
| Power | 115V or 220V |
| Safety | Emergency Stop |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marking |
| Service | ON-call service |
OligoMaker X96
The DNA / RNA Synthesizer OligoMaker X96 (OM-X96) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.
- OligoMaker X96 is compact (100cm x 55cm x 60cm) and easy to operate.
- OligoMaker X96 can synthesize up to 96 oligos (20-mer) in about 2.5 hour.
- OligoMaker X96 is ideal for research institutions that require increased flexibility to handle primers and probes, e.g smaller diagnostic company.
- Larger oligo production facilities can integrate the OligoMaker X96 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
- Direct injection of reagent from the valve into the synthesis column or plates.
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | From 1 to 96 primers in one run |
| Scale of synthesis | 10, 50, 200, 1000 and 3000 nmol scale |
| Support material | CPG or Universal support in standard columns or 96-well plate |
| Standard equipment for amidites | 4 x 200-ml bottles + 2 x 10-ml |
| Up to 8 Extra amidite positions | 10-ml bottles |
| Standard 2 activator positions | Activating in parallel |
| Standard 2 wash positions | Washing in parallel |
| Standard 1 deblocking positions | Deblocking |
| Standard 1 Ox position | Oxidizer |
| Standard Cap A position | Capping simultaneously with Cap B |
| Standard Cap B position | Capping simultaneously with Cap A |
| Free position | Custom specified |
| Automatic Wash and Purge System | Automatically wash and purge all nozzles after synthesis |
| Pressure on reagents | Each bottle can be pressurized and depressurized individually |
| Only one gas connection | One gas for making pressure in the bottles and purging during synthesis |
| Instrument – and Cleaning | 1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within a few minutes |
| Spare parts | Spare parts are in stock |
| Power | 115V or 220V |
| Safety | Emergency Stop |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marking |
| Service | ON-call service |
OligoMaker X192
The DNA / RNA Synthesizer OligoMaker X192 (OM-X192) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.
- OligoMaker X192 is compact (100cm x 55cm x 60cm) and easy to operate.
- OligoMaker X192 can synthesize up to 192 oligos (20-mer) in about 3 hour.
- OligoMaker X192 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
- Larger oligo production facilities can integrate the OligoMaker X192 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
- Direct injection of reagent from the valve into the synthesis column or plates.
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | From 1 to 192 primers in one run |
| Scale of synthesis | 10, 50, 200, 1000 and 3000 nmol scale |
| Support material | CPG or Universal support in 192 x standard columns or 2 x 96-well plates |
| Standard equipment for amidites | 4 x 200-ml bottles |
| Up to 6 Extra amidite positions | 30 or 60-ml bottles |
| Standard 1 activator positions | Activating in parallel |
| Standard 2 wash positions | Washing in parallel |
| Standard 1 deblocking positions | Deblocking |
| Standard 1 Ox position | Oxidizer |
| Standard Cap A position | Capping simultaneously with Cap B |
| Standard Cap B position | Capping simultaneously with Cap A |
| Free position | Custom specified |
| Automatic Wash and Purge System | Automatically wash and purge all nozzles after synthesis |
| Pressure on reagents | Each bottle can be pressurized and depressurized individually |
| Only one gas connection | One gas for making pressure in the bottles and purging during synthesis |
| Instrument – and Cleaning | 1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within some minutes |
| Spare parts | Spare parts are in stock |
| Power | 110/115V or 220/240V |
| Safety | Emergency Stop |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marking |
| Service | ON-call service |
OligoMaker 384
The DNA / RNA Synthesizer OligoMaker 384 (OM-384) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.
- OligoMaker 384 is compact (1160cm x 60cm x 60cm) and easy to operate.
- OligoMaker 384 can synthesize up to 384 oligos (20-mer) in about 4 hour using 384-well plates.
- OligoMaker 384 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
- Larger oligo production facilities can integrate the OligoMaker 384 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
- Direct injection of reagent from the valve into the synthesis column or plates.
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | 1 x 384-well plates – up to 384 primers in one run |
| Scale of synthesis | 5, 10, 25 and 50 nmol scale |
| Support material | Universal support |
| Standard Phosphoramidite positions | 4 x 0.5L or 1L bottles |
| Up to 5 Extra amidite positions | 180-ml bottles |
| Standard 2 activator positions | Activating in parallel – 2.5L or 4L |
| Standard 2 wash positions | Washing in parallel – 2.5L or 4L |
| Standard 2 deblocking positions | Deblocking – 2.5L or 4L |
| Standard 2 Ox positions | Oxidizer – 2.5L or 4L |
| Standard Cap A position | Capping simultaneously with Cap B – 2.5L or 4L |
| Standard Cap B position | Capping simultaneously with Cap A – 2.5L or 4L |
| Standard DEA position | Deprotection – 450-ml |
| Free position | Custom specified |
| Automatic Wash and Purge System | Automatically wash and purge all nozzles after synthesis |
| Pressure on reagents | Each bottle can be pressurized and depressurized individually |
| Only one gas connection | One gas for making pressure in the bottles and purging during synthesis |
| Instrument – and Cleaning | 1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within a few minutes |
| Spare parts | Spare parts are in stock |
| Power | 110/155V or 220/240V |
| Safety | Emergency Stop |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marking |
| Service | ON-call service |
OligoMaker 768
The DNA / RNA Synthesizer OligoMaker 768 (OM-768) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.
- OligoMaker 768 is compact (1160cm x 60cm x 60cm) and easy to operate.
- OligoMaker 768 can synthesize up to 768 oligos (20-mer) in about 4 hour using 2 x 384-well plates.
- OligoMaker 768 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
- Larger oligo production facilities can integrate the OligoMaker 768 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
- Direct injection of reagent from the valve into the synthesis column or plates.
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | 1 – 2 x 384-well plates – up to 768 primers in one run |
| Scale of synthesis | 5, 10, 25 and 50 nmol scale |
| Support material | Universal support |
| Standard Phosphoramidite positions | 4 x 0.5L or 1L bottles |
| Standard 2 activator positions | Activating in parallel – 2.5L or 4L |
| Standard 2 wash positions | Washing in parallel – 2.5L or 4L |
| Standard 2 deblocking positions | Deblocking in parallel – 2.5L or 4L |
| Standard 2 Ox positions | Oxidizer – 2.5L or 4L |
| Standard Cap A position | Capping simultaneously with Cap B – 2.5L or 4L |
| Standard Cap B position | Capping simultaneously with Cap A – 2.5L or 4L |
| Option DEA position | Deprotection – 450-ml |
| Free position | Custom specified |
| Automatic Purge and Wash System | Automatically wash and purge all nozzles after synthesis |
| Pressure on reagents | Each bottle can be pressurized and depressurized individually |
| Only one gas connection | One gas for making pressure in the bottles and purging during synthesis |
| Instrument – and Cleaning | 1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within a few minutes |
| Spare parts | Spare parts are in stock |
| Power | 110/115V or 220/240V |
| Safety | Emergency Stop |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marking |
| Service | ON-call service |
OligoMaker 1536
The DNA / RNA Synthesizer OligoMaker 1536 (OM-1536) is the largest oligonucleotide synthesizers on the market. The synthesizer has a total of 16 channels with 4 base positions.
- OligoMaker 1536 is compact (1160cm x 60cm x 60cm) and easy to operate.
- OligoMaker 1536 can synthesize up to 1536 oligos (20-mer) in about 5 hour.
- OligoMaker 1536 is ideal for larger labs and research institutions that require higher synthesis capacity, offering our highest yield and increased flexibility to handle larger workloads.
- Larger oligo production facilities can integrate the OligoMaker 1536 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
- Direct injection of reagent from the valve into the synthesis column or plates
- You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
| Subject | Description |
|---|---|
| Capacity | 1 – 4 x 384-well plates – 1 – 1536 primers in one run |
| Scale of synthesis | 5, 10 and 25 nmol scale |
| Support material | Universal support |
| Standard equipment for amidites | 4 x 1L bottles |
| Standard Bottles for reagent | 7 x 4L bottles |
| Standard 2 activator positions | Activating in parallel |
| Standard 2 wash positions | Washing in parallel |
| Standard 2 deblocking positions | Deblocking in parallel |
| Standard 2 Ox position | Oxidizer in parallel |
| Standard Cap A position | Capping simultaneously with Cap B |
| Standard Cap B position | Capping simultaneously with Cap A |
| Automatic Wash and Purge System | Automatically wash and purge all nuzzles after synthesis |
| Pressure on reagents | Each bottle can be pressurized and depressurized individually |
| Only one gas connection | One gas for making pressure in the bottles and purging during |
| Instrument – and Cleaning | 1160 x 600 x 600 mm (L x W x H) – Design with large straight surfaces |
| Maintenance | Replacing valves and tubing within a few minutes |
| Spare parts | Spare parts are in stock |
| Power | 110/115V or 220/240V |
| Safety | Emergency Stop |
| QC | All instruments undergo a strict quality control process in our lab |
| Certification | CE marked |
| Service | ON-call service |