DNA Synthesizer Oligo X Platform

About OligoMaker X Platform

The OligoMaker X DNA Synthesizer Platform enables you to synthesize 12 to 1536 primers and probes simultaneously in a single run, utilizing a 96 or 384-well plate format for maximum efficiency. After synthesis, the column holder facilitates a seamless transition to the next step in the workup process.

A key feature of the OligoMaker X is our innovative “weekend wash” system. After each synthesis, all valves, tubing, and nozzles are automatically flushed with acetonitrile, extending the lifespan of the components and preventing clogging in the tubing—ensuring reliable, uninterrupted performance.

Key Features

Synthesis Columns or Plates
User-friendly operation
Low Maintenance
Small footprint

DNA Synthesizer OligoMaker OM-X12

The DNA / RNA Synthesizer OligoMaker OM-X12/6 (OM-X12) is a flexible 12-channel oligonucleotide synthesizer with 6 base positions. Can easily be upgraded to 14 base positions.

OligoMaker OM-X12 is compact (80cm x 35cm x 35cm) and easy to operate.
OligoMaker OM-X12 can synthesize up to 12 oligos (20-mer) in about 1 hour.
OligoMaker OM-X12 is suitable for the smaller labs at the universities, where you might have a limited amount of amidite solution.
Larger oligo houses can also benefit from this small and flexible synthesizer among all the high throughput machines.
Direct injection of reagent from the valve into the synthesis column.
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification Download Specification (US)

Subject	Description
Capacity	From 1 to 12 primers in one run – all +150-mer
Scale of synthesis	10, 50nmol, 0.2, 1 and 3μmol scale
Support material	CPG or Universal support in standard columns
Standard equipment for amidites	4 x 60-ml bottles + 2 x 10-ml
Up to 8 Extra amidite positions	10-ml bottles
Standard 1 wash position	Acetonitrile – 450-ml
Standard 1 activator position	Activator – 180-ml
Standard 1 deblocking position	Deblocking – 450-ml
Standard 1 Ox position	Oxidizer – 180-ml
Standard Cap A position	Capping simultaneously with Cap B – 180-ml
Standard Cap B position	Capping simultaneously with Cap A – 180-ml
Ox2 position	Option – 30-ml bottle
Trityl monitoring	Trityl observation is possible after each cycle, coupling yield 99.0-99.5%
Only one gas connection	One gas for making pressure in the bottles and purging during synthesis
Instrument dimensions	800 x 350 x 350 mm (L x W x H)
Cleaning	Design with large straight surfaces
Maintenance	Replacing valves and tubing within a few minutes
Spare parts	Spare parts are in stock
Power	110/115V or 220/240V
Safety	Overflowing by accident is directed to waste container
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marking
Service	On-call service

DNA Synthesizer OligoMaker OM-X48

The DNA / RNA Synthesizer OligoMaker OM-X48 (OM-X48) is a flexible oligonucleotide synthesizer with 4 base positions. Can easily be upgraded with 5 base positions

OligoMaker OM-X48 is compact (100cm x 55cm x 60cm) and easy to operate.
OligoMaker OM-X48 can synthesize up to 48 oligos (20-mer) in about 2 hour.
OligoMaker OM-X48 is ideal for research institutions that require increased flexibility to handle primers and probes, e.g smaller diagnostic company.
Larger oligo production facilities can integrate the OligoMaker OM-X48 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
Direct injection of reagent from the valve into the synthesis column or plates.
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification, Download Specification (US)

Subject	Description
Capacity	From 1 to 48 primers in one run – all +150-mer
Scale of synthesis	10, 50nmol, 0.2, 1 and 3μmol scale
Support material	CPG or Universal support in standard columns
Standard equipment for amidites	4 x 120-ml bottles + 2 x 10-ml
Up to 8 Extra amidite positions	10-ml bottles
Standard 2 activator positions	Activating in parallel
Standard 1 wash position	Washing
Standard 1 deblocking positions	Deblocking
Standard 1 Ox position	Oxidizer
Standard Cap A position	Capping simultaneously with Cap B
Standard Cap B position	Capping simultaneously with Cap A
Free position	Custom specified
Trityl monitoring	Trityl observation is possible after each cycle, coupling yield 99.0-99.5%
Automatic Wash and Purge System	Automatically wash and purge all nozzles after synthesis
Pressure on reagents	Each bottle can be pressurized and depressurized individually
Only one gas connection	One gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning	1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
Maintenance	Replacing valves and tubing within a few minutes
Spare parts	Spare parts are in stock
Power	115V or 220V
Safety	Emergency Stop
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marking
Service	ON-call service

DNA Synthesizer OligoMaker OM-X96

The DNA / RNA Synthesizer OligoMaker X96 (OM-X96) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

Front view of DNA synthesizer OligoMaker OM x192

OligoMaker OM-X96 is compact (100cm x 55cm x 60cm) and easy to operate.
OligoMaker OM-X96 can synthesize up to 96 oligos (20-mer) in about 2.5 hour.
OligoMaker OM-X96 is ideal for research institutions that require increased flexibility to handle primers and probes, e.g smaller diagnostic company.
Larger oligo production facilities can integrate the OligoMaker OM-X96 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
Direct injection of reagent from the valve into the synthesis column or plates.
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification, Download Specification (US)

Subject	Description
Capacity	From 1 to 96 primers in one run
Scale of synthesis	10, 50, 200, 1000 and 3000 nmol scale
Support material	CPG or Universal support in standard columns or 96-well plate
Standard equipment for amidites	4 x 200-ml bottles + 2 x 10-ml
Up to 8 Extra amidite positions	10-ml bottles
Standard 2 activator positions	Activating in parallel
Standard 2 wash positions	Washing in parallel
Standard 1 deblocking positions	Deblocking
Standard 1 Ox position	Oxidizer
Standard Cap A position	Capping simultaneously with Cap B
Standard Cap B position	Capping simultaneously with Cap A
Free position	Custom specified
Automatic Wash and Purge System	Automatically wash and purge all nozzles after synthesis
Pressure on reagents	Each bottle can be pressurized and depressurized individually
Only one gas connection	One gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning	1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
Maintenance	Replacing valves and tubing within a few minutes
Spare parts	Spare parts are in stock
Power	115V or 220V
Safety	Emergency Stop
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marking
Service	ON-call service

DNA Synthesizer OligoMaker OM-X192

The DNA / RNA Synthesizer OligoMaker X192 (OM-X192) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

OligoMaker OM-X192 is compact (100cm x 55cm x 60cm) and easy to operate.
OligoMaker OM-X192 can synthesize up to 192 oligos (20-mer) in about 3 hour.
OligoMaker OM-X192 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
Larger oligo production facilities can integrate the OligoMaker OM-X192 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
Direct injection of reagent from the valve into the synthesis column or plates.
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification, Download Specification (US)

Subject	Description
Capacity	From 1 to 192 primers in one run
Scale of synthesis	10, 50, 200, 1000 and 3000 nmol scale
Support material	CPG or Universal support in 192 x standard columns or 2 x 96-well plates
Standard equipment for amidites	4 x 200-ml bottles
Up to 6 Extra amidite positions	30 or 60-ml bottles
Standard 1 activator positions	Activating in parallel
Standard 2 wash positions	Washing in parallel
Standard 1 deblocking positions	Deblocking
Standard 1 Ox position	Oxidizer
Standard Cap A position	Capping simultaneously with Cap B
Standard Cap B position	Capping simultaneously with Cap A
Free position	Custom specified
Automatic Wash and Purge System	Automatically wash and purge all nozzles after synthesis
Pressure on reagents	Each bottle can be pressurized and depressurized individually
Only one gas connection	One gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning	1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
Maintenance	Replacing valves and tubing within some minutes
Spare parts	Spare parts are in stock
Power	110/115V or 220/240V
Safety	Emergency Stop
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marking
Service	ON-call service

DNA Synthesizer OligoMaker 384

The DNA / RNA Synthesizer OligoMaker 384 (OM-384) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

Front view of DNA synthesizer OligoMaker OM 384

OligoMaker OM-384 is compact (1160cm x 60cm x 60cm) and easy to operate.
OligoMaker OM-384 can synthesize up to 384 oligos (20-mer) in about 4 hour using 384-well plates.
OligoMaker OM-384 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
Larger oligo production facilities can integrate the OligoMaker OM-384 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
Direct injection of reagent from the valve into the synthesis column or plates.
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification, Download Specification (US)

Subject	Description
Capacity	1 x 384-well plates – up to 384 primers in one run
Scale of synthesis	5, 10, 25 and 50 nmol scale
Support material	Universal support
Standard Phosphoramidite positions	4 x 0.5L or 1L bottles
Up to 5 Extra amidite positions	180-ml bottles
Standard 2 activator positions	Activating in parallel – 2.5L or 4L
Standard 2 wash positions	Washing in parallel – 2.5L or 4L
Standard 2 deblocking positions	Deblocking – 2.5L or 4L
Standard 2 Ox positions	Oxidizer – 2.5L or 4L
Standard Cap A position	Capping simultaneously with Cap B – 2.5L or 4L
Standard Cap B position	Capping simultaneously with Cap A – 2.5L or 4L
Standard DEA position	Deprotection – 450-ml
Free position	Custom specified
Automatic Wash and Purge System	Automatically wash and purge all nozzles after synthesis
Pressure on reagents	Each bottle can be pressurized and depressurized individually
Only one gas connection	One gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning	1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
Maintenance	Replacing valves and tubing within a few minutes
Spare parts	Spare parts are in stock
Power	110/155V or 220/240V
Safety	Emergency Stop
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marking
Service	ON-call service

DNA Synthesizer OligoMaker 768

The DNA / RNA Synthesizer OligoMaker 768 (OM-768) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

Front view of DNA synthesizer oligomaker om 768

OligoMaker OM-768 is compact (1160cm x 60cm x 60cm) and easy to operate.
OligoMaker OM-768 can synthesize up to 768 oligos (20-mer) in about 4 hour using 2 x 384-well plates.
OligoMaker OM-768 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
Larger oligo production facilities can integrate the OligoMaker OM-768 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
Direct injection of reagent from the valve into the synthesis column or plates.
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification Download Specification (US)

Subject	Description
Capacity	1 – 2 x 384-well plates – up to 768 primers in one run
Scale of synthesis	5, 10, 25 and 50 nmol scale
Support material	Universal support
Standard Phosphoramidite positions	4 x 0.5L or 1L bottles
Standard 2 activator positions	Activating in parallel – 2.5L or 4L
Standard 2 wash positions	Washing in parallel – 2.5L or 4L
Standard 2 deblocking positions	Deblocking in parallel – 2.5L or 4L
Standard 2 Ox positions	Oxidizer – 2.5L or 4L
Standard Cap A position	Capping simultaneously with Cap B – 2.5L or 4L
Standard Cap B position	Capping simultaneously with Cap A – 2.5L or 4L
Option DEA position	Deprotection – 450-ml
Free position	Custom specified
Automatic Purge and Wash System	Automatically wash and purge all nozzles after synthesis
Pressure on reagents	Each bottle can be pressurized and depressurized individually
Only one gas connection	One gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning	1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
Maintenance	Replacing valves and tubing within a few minutes
Spare parts	Spare parts are in stock
Power	110/115V or 220/240V
Safety	Emergency Stop
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marking
Service	ON-call service

DNA Synthesizer OligoMaker 1536

The DNA / RNA Synthesizer OligoMaker 1536 (OM-1536) is the largest oligonucleotide synthesizers on the market. The synthesizer has a total of 16 channels with 4 base positions.

Front view of DNA synthesizer Oligomaker om 1536

OligoMaker OM-1536 is compact (1160cm x 60cm x 60cm) and easy to operate.
OligoMaker OM-1536 can synthesize up to 1536 oligos (20-mer) in about 5 hour.
OligoMaker OM-1536 is ideal for larger labs and research institutions that require higher synthesis capacity, offering our highest yield and increased flexibility to handle larger workloads.
Larger oligo production facilities can integrate the OligoMaker OM-1536 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
Direct injection of reagent from the valve into the synthesis column or plates
You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
Download Specification, Download Specification (US)

Subject	Description
Capacity	1 – 4 x 384-well plates – 1 – 1536 primers in one run
Scale of synthesis	5, 10 and 25 nmol scale
Support material	Universal support
Standard equipment for amidites	4 x 1L bottles
Standard Bottles for reagent	7 x 4L bottles
Standard 2 activator positions	Activating in parallel
Standard 2 wash positions	Washing in parallel
Standard 2 deblocking positions	Deblocking in parallel
Standard 2 Ox position	Oxidizer in parallel
Standard Cap A position	Capping simultaneously with Cap B
Standard Cap B position	Capping simultaneously with Cap A
Automatic Wash and Purge System	Automatically wash and purge all nuzzles after synthesis
Pressure on reagents	Each bottle can be pressurized and depressurized individually
Only one gas connection	One gas for making pressure in the bottles and purging during
Instrument – and Cleaning	1160 x 600 x 600 mm (L x W x H) – Design with large straight surfaces
Maintenance	Replacing valves and tubing within a few minutes
Spare parts	Spare parts are in stock
Power	110/115V or 220/240V
Safety	Emergency Stop
QC	All instruments undergo a strict quality control process in our lab
Certification	CE marked
Service	ON-call service

DNA Synthesizer Oligo X Platform

About OligoMaker X Platform

Key Features

DNA Synthesizer OligoMaker OM-X12

DNA Synthesizer OligoMaker OM-X48

DNA Synthesizer OligoMaker OM-X96

DNA Synthesizer OligoMaker OM-X192

DNA Synthesizer OligoMaker 384

DNA Synthesizer OligoMaker 768

DNA Synthesizer OligoMaker 1536

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OligoMaker ApS

Headquarter, Denmark

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