Oligo X Platform

About OligoMaker X Platform

The OligoMaker X Platform enables you to synthesize 12 to 1536 primers and probes simultaneously in a single run, utilizing a 96 or 384-well plate format for maximum efficiency. After synthesis, the column holder facilitates a seamless transition to the next step in the workup process.

A key feature of the OligoMaker X is our innovative “weekend wash” system. After each synthesis, all valves, tubing, and nozzles are automatically flushed with acetonitrile, extending the lifespan of the components and preventing clogging in the tubing—ensuring reliable, uninterrupted performance.

Key Features

  • Synthesis Columns or Plates
  • User-friendly operation
  • Low Maintenance
  • Small footprint

OligoMaker X12

The DNA / RNA Synthesizer OligoMaker X12/6 (OM-X12) is a flexible 12-channel oligonucleotide synthesizer with 6 base positions. Can easily be upgraded to 14 base positions.

  • OligoMaker X12 is compact (80cm x 35cm x 35cm) and easy to operate.
  • OligoMaker X12 can synthesize up to 12 oligos (20-mer) in about 1 hour.
  • OligoMaker X12 is suitable for the smaller labs at the universities, where you might have a limited amount of amidite solution.
  • Larger oligo houses can also benefit from this small and flexible synthesizer among all the high throughput machines.
  • Direct injection of reagent from the valve into the synthesis column.
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
CapacityFrom 1 to 12 primers in one run – all +150-mer
Scale of synthesis10, 50nmol, 0.2, 1 and 3μmol scale
Support materialCPG or Universal support in standard columns
Standard equipment for amidites4 x 60-ml bottles + 2 x 10-ml
Up to 8 Extra amidite positions10-ml bottles
Standard 1 wash positionAcetonitrile – 450-ml
Standard 1 activator positionActivator – 180-ml
Standard 1 deblocking positionDeblocking – 450-ml
Standard 1 Ox positionOxidizer – 180-ml
Standard Cap A positionCapping simultaneously with Cap B – 180-ml
Standard Cap B positionCapping simultaneously with Cap A – 180-ml
Ox2 positionOption – 30-ml bottle
Trityl monitoringTrityl observation is possible after each cycle, coupling yield 99.0-99.5%
Only one gas connectionOne gas for making pressure in the bottles and purging during synthesis
Instrument dimensions800 x 350 x 350 mm (L x W x H)
CleaningDesign with large straight surfaces
MaintenanceReplacing valves and tubing within a few minutes
Spare partsSpare parts are in stock
Power110/115V or 220/240V
SafetyOverflowing by accident is directed to waste container
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marking
ServiceOn-call service

OligoMaker X48

The DNA / RNA Synthesizer OligoMaker X48 (OM-X48) is a flexible oligonucleotide synthesizer with 4 base positions. Can easily be upgraded with 5 base positions

  • OligoMaker X48 is compact (100cm x 55cm x 60cm) and easy to operate.
  • OligoMaker X48 can synthesize up to 48 oligos (20-mer) in about 2 hour.
  • OligoMaker X48 is ideal for research institutions that require increased flexibility to handle primers and probes, e.g smaller diagnostic company.
  • Larger oligo production facilities can integrate the OligoMaker X48 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
  • Direct injection of reagent from the valve into the synthesis column or plates.
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
CapacityFrom 1 to 48 primers in one run – all +150-mer
Scale of synthesis10, 50nmol, 0.2, 1 and 3μmol scale
Support materialCPG or Universal support in standard columns
Standard equipment for amidites4 x 120-ml bottles + 2 x 10-ml
Up to 8 Extra amidite positions10-ml bottles
Standard 2 activator positionsActivating in parallel
Standard 1 wash positionWashing
Standard 1 deblocking positionsDeblocking
Standard 1 Ox positionOxidizer
Standard Cap A positionCapping simultaneously with Cap B
Standard Cap B positionCapping simultaneously with Cap A
Free positionCustom specified
Trityl monitoringTrityl observation is possible after each cycle, coupling yield 99.0-99.5%
Automatic Wash and Purge SystemAutomatically wash and purge all nozzles after synthesis
Pressure on reagentsEach bottle can be pressurized and depressurized individually
Only one gas connectionOne gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
MaintenanceReplacing valves and tubing within a few minutes
Spare partsSpare parts are in stock
Power115V or 220V
SafetyEmergency Stop
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marking
ServiceON-call service

OligoMaker X96

The DNA / RNA Synthesizer OligoMaker X96 (OM-X96) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

  • OligoMaker X96 is compact (100cm x 55cm x 60cm) and easy to operate.
  • OligoMaker X96 can synthesize up to 96 oligos (20-mer) in about 2.5 hour.
  • OligoMaker X96 is ideal for research institutions that require increased flexibility to handle primers and probes, e.g smaller diagnostic company.
  • Larger oligo production facilities can integrate the OligoMaker X96 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
  • Direct injection of reagent from the valve into the synthesis column or plates.
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
CapacityFrom 1 to 96 primers in one run
Scale of synthesis10, 50, 200, 1000 and 3000 nmol scale
Support materialCPG or Universal support in standard columns or 96-well plate
Standard equipment for amidites4 x 200-ml bottles + 2 x 10-ml
Up to 8 Extra amidite positions10-ml bottles
Standard 2 activator positionsActivating in parallel
Standard 2 wash positionsWashing in parallel
Standard 1 deblocking positionsDeblocking
Standard 1 Ox positionOxidizer
Standard Cap A positionCapping simultaneously with Cap B
Standard Cap B positionCapping simultaneously with Cap A
Free positionCustom specified
Automatic Wash and Purge SystemAutomatically wash and purge all nozzles after synthesis
Pressure on reagentsEach bottle can be pressurized and depressurized individually
Only one gas connectionOne gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
MaintenanceReplacing valves and tubing within a few minutes
Spare partsSpare parts are in stock
Power115V or 220V
SafetyEmergency Stop
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marking
ServiceON-call service

OligoMaker X192

The DNA / RNA Synthesizer OligoMaker X192 (OM-X192) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

  • OligoMaker X192 is compact (100cm x 55cm x 60cm) and easy to operate.
  • OligoMaker X192 can synthesize up to 192 oligos (20-mer) in about 3 hour.
  • OligoMaker X192 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
  • Larger oligo production facilities can integrate the OligoMaker X192 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
  • Direct injection of reagent from the valve into the synthesis column or plates.
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
CapacityFrom 1 to 192 primers in one run
Scale of synthesis10, 50, 200, 1000 and 3000 nmol scale
Support materialCPG or Universal support in 192 x standard columns or 2 x 96-well plates
Standard equipment for amidites4 x 200-ml bottles
Up to 6 Extra amidite positions30 or 60-ml bottles
Standard 1 activator positionsActivating in parallel
Standard 2 wash positionsWashing in parallel
Standard 1 deblocking positionsDeblocking
Standard 1 Ox positionOxidizer
Standard Cap A positionCapping simultaneously with Cap B
Standard Cap B positionCapping simultaneously with Cap A
Free positionCustom specified
Automatic Wash and Purge SystemAutomatically wash and purge all nozzles after synthesis
Pressure on reagentsEach bottle can be pressurized and depressurized individually
Only one gas connectionOne gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
MaintenanceReplacing valves and tubing within some minutes
Spare partsSpare parts are in stock
Power110/115V or 220/240V
SafetyEmergency Stop
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marking
ServiceON-call service

OligoMaker 384

The DNA / RNA Synthesizer OligoMaker 384 (OM-384) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

  • OligoMaker 384 is compact (1160cm x 60cm x 60cm) and easy to operate.
  • OligoMaker 384 can synthesize up to 384 oligos (20-mer) in about 4 hour using 384-well plates.
  • OligoMaker 384 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
  • Larger oligo production facilities can integrate the OligoMaker 384 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
  • Direct injection of reagent from the valve into the synthesis column or plates.
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
Capacity1 x 384-well plates – up to 384 primers in one run
Scale of synthesis5, 10, 25 and 50 nmol scale
Support materialUniversal support
Standard Phosphoramidite positions4 x 0.5L or 1L bottles
Up to 5 Extra amidite positions180-ml bottles
Standard 2 activator positionsActivating in parallel – 2.5L or 4L
Standard 2 wash positionsWashing in parallel – 2.5L or 4L
Standard 2 deblocking positionsDeblocking – 2.5L or 4L
Standard 2 Ox positionsOxidizer – 2.5L or 4L
Standard Cap A positionCapping simultaneously with Cap B – 2.5L or 4L
Standard Cap B positionCapping simultaneously with Cap A – 2.5L or 4L
Standard DEA positionDeprotection – 450-ml
Free positionCustom specified
Automatic Wash and Purge SystemAutomatically wash and purge all nozzles after synthesis
Pressure on reagentsEach bottle can be pressurized and depressurized individually
Only one gas connectionOne gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
MaintenanceReplacing valves and tubing within a few minutes
Spare partsSpare parts are in stock
Power110/155V or 220/240V
SafetyEmergency Stop
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marking
ServiceON-call service

OligoMaker 768

The DNA / RNA Synthesizer OligoMaker 768 (OM-768) has a total of 19 channels with 4 base positions. Optional upgrade to 5 additional base positions.

  • OligoMaker 768 is compact (1160cm x 60cm x 60cm) and easy to operate.
  • OligoMaker 768 can synthesize up to 768 oligos (20-mer) in about 4 hour using 2 x 384-well plates.
  • OligoMaker 768 is ideal for larger labs and research institutions that require higher synthesis capacity, offering double the yield and increased flexibility to handle larger workloads.
  • Larger oligo production facilities can integrate the OligoMaker 768 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
  • Direct injection of reagent from the valve into the synthesis column or plates.
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
Capacity1 – 2 x 384-well plates – up to 768 primers in one run
Scale of synthesis5, 10, 25 and 50 nmol scale
Support materialUniversal support
Standard Phosphoramidite positions4 x 0.5L or 1L bottles
Standard 2 activator positionsActivating in parallel – 2.5L or 4L
Standard 2 wash positionsWashing in parallel – 2.5L or 4L
Standard 2 deblocking positionsDeblocking in parallel – 2.5L or 4L
Standard 2 Ox positionsOxidizer – 2.5L or 4L
Standard Cap A positionCapping simultaneously with Cap B – 2.5L or 4L
Standard Cap B positionCapping simultaneously with Cap A – 2.5L or 4L
Option DEA positionDeprotection – 450-ml
Free positionCustom specified
Automatic Purge and Wash SystemAutomatically wash and purge all nozzles after synthesis
Pressure on reagentsEach bottle can be pressurized and depressurized individually
Only one gas connectionOne gas for making pressure in the bottles and purging during synthesis
Instrument – and Cleaning1000 x 550 x 600 mm (L x W x H) – Design with large straight surfaces
MaintenanceReplacing valves and tubing within a few minutes
Spare partsSpare parts are in stock
Power110/115V or 220/240V
SafetyEmergency Stop
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marking
ServiceON-call service

OligoMaker 1536

The DNA / RNA Synthesizer OligoMaker 1536 (OM-1536) is the largest oligonucleotide synthesizers on the market. The synthesizer has a total of 16 channels with 4 base positions.

  • OligoMaker 1536 is compact (1160cm x 60cm x 60cm) and easy to operate.
  • OligoMaker 1536 can synthesize up to 1536 oligos (20-mer) in about 5 hour.
  • OligoMaker 1536 is ideal for larger labs and research institutions that require higher synthesis capacity, offering our highest yield and increased flexibility to handle larger workloads.
  • Larger oligo production facilities can integrate the OligoMaker 1536 alongside their high-throughput systems for increased output, while still benefiting from its versatile and efficient design.
  • Direct injection of reagent from the valve into the synthesis column or plates
  • You can visually monitor the synthesis in real-time through the observation windows, ensuring each step runs smoothly.
SubjectDescription
Capacity1 – 4 x 384-well plates   –   1 – 1536 primers in one run
Scale of synthesis5, 10 and 25 nmol scale
Support materialUniversal support
Standard equipment for amidites4 x 1L bottles
Standard Bottles for reagent7 x 4L bottles
Standard 2 activator positionsActivating in parallel
Standard 2 wash positionsWashing in parallel
Standard 2 deblocking positionsDeblocking in parallel
Standard 2 Ox positionOxidizer in parallel
Standard Cap A positionCapping simultaneously with Cap B
Standard Cap B positionCapping simultaneously with Cap A
Automatic Wash and Purge SystemAutomatically wash and purge all nuzzles after synthesis
Pressure on reagentsEach bottle can be pressurized and depressurized individually
Only one gas connectionOne gas for making pressure in the bottles and purging during
Instrument – and Cleaning1160 x 600 x 600 mm (L x W x H) – Design with large straight surfaces
MaintenanceReplacing valves and tubing within a few minutes
Spare partsSpare parts are in stock
Power110/115V or 220/240V
SafetyEmergency Stop
QCAll instruments undergo a strict quality control process in our lab
CertificationCE marked
ServiceON-call service

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